Diabetes is a genetically heterogeneous disease. Therefore, according to its pathophysiological and clinical characteristics, it can be divided into four types: type 1, type 2, other special types and gestational diabetes, which can be also classified into monogenic form and polygenic susceptibility form of diabetes according to mutations or variations in causing genes. As the research progress of molecular genetics, mutated pathogenic genes of familial hereditary diabetes mellitus are gradually clarified, the “precision medicine” time for genetic diagnosis and individualized drug targeted therapy of special types of diabetes, which is functionally characterized by genetic defects of islet β cells with monogenic mutations, has come! Studies for special types of diabetes, as model of polygenic susceptibility forms of diabetes, will accelerate the latter’s development of precision medicine. Thus, for the teaching system of medical undergraduate students, it is imperative to study the reform in the integration of genetics and diabetology in the learning curriculum systems.
Integration; Genetics; Diabetology; Precision medicine; New teaching mode