Comparison the clinical application of exhaled nitric oxide (FeNO) level and pulmonary function for the patients with bronchial asthma

Yu-feng Zhang, Xu-wei Wu

Abstract


Objective:  Comparison the test result of exhaled nitric oxide (FeNO) level and pulmonary function for the patients with bronchial asthma. We will find the fast、efficient method for early diagnosis of bronchial asthma. Methods:I determined 90 cases of suspected patients of bronchial asthma with Foundation pulmonary function、Exhaled nitric oxide measurement and Brinchial provocation test. Results: The results of 90 cases Foundation pulmonary function are normal, the cases of FeNO increased are 86 among them, the positive rate is 95%;the Positives of brinchial provocation test are 75 among them, the positive rate is 83%. FeNO and bronchial provocation test showed a moderate positive correlation. The timeliness and safety of FeNO determination is better than that of bronchial provocation test, and the difference was statistically significant (P<0.05). Conclusion: A correlation between FeNO and airway reactivity. IF we compared exhaled nitric oxide and bronchial provocation test for early diagnosis of bronchial asthma,FeNO is simple, safe, fast, and it is easy for patients to accept the advantages. But FeNO is affected by many factors, it’s reference value is also no uniform standards, the further research is needed. For non allergic asthma patients, although FeNO determination is normal, we cannot exclude asthma, determination of BHR still need for further definite diagnosis.

Keywords


Nitric oxide; Pulmonary function; Asthma

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DOI: http://dx.doi.org/10.14725/gjtm.v2n2a496

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Global Journal of Traditional Medicine 

ISSN 2308-5665 (Print)  ISSN ****-**** (Online)