Plasma homocysteine(Hcy) and D-dimer levels in patients with differernt subtype of acute cerebral infarction: a correlation study
Purpose-To study plasma homocysteine(Hcy)/D-dimer levels in patients with differernt subtype of acute cerebral infarction for early etiology diagnosis. Methods: The subjects were 246 acute cerebral infarction patients in the first 24 hours of stroke onset at our hospital. We divided them into large –artery atherosclerosis(LAA) group(n=66), small artery occlusion(SAO) group(n=76), cardio embolism(CE) group(n=40),stroke of other demonstrated etiology(SOE) group (n=11)and stroke of other undemonstrated etiology(SUE) group(n=51) according to the TOAST classification. Plasma homocysteine and D-diamer were determined within the first 24 hours of admission, the differences in subgroups and control group(n=121) were analyzed. Results:Plasma homocysteine levels in LAA group were signficantly higher than other groups(P<0.05), no differences in non-LAA groups(P>0.05);Plasma D-diamer levels in CE group were significant higher than other groups(P<0.05), no differences in non-CE groups(P>0.05). Conclusions: Plasma homocysteine and D-diamer level are associated with subtypes of acute cerebral infarction, and it contributed to early classification diagnosis and individual treatment of patients with acute cerebral infarction.
Cerebralinfarction; Homocysteinemia(Hcy); D-dimer;TOASTclassification
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Global Journal of Traditional Medicine
ISSN 2308-5665 (Print) ISSN ****-**** (Online)