Plasma homocysteine(Hcy) and D-dimer levels in patients with differernt subtype of acute cerebral infarction: a correlation study

Li Ming, Da-lin Yu, Xian-yong Tang, Xian-wen Fang, Xing Yong, Hui-ying Li, Jun Xiao

Abstract


Purpose-To study plasma homocysteine(Hcy)/D-dimer levels in patients with differernt subtype of acute cerebral infarction for early etiology diagnosis. Methods: The subjects were 246 acute cerebral infarction patients in the first 24 hours of stroke onset at our hospital. We divided them into large –artery atherosclerosis(LAA) group(n=66), small artery occlusion(SAO) group(n=76), cardio embolism(CE) group(n=40),stroke of other demonstrated etiology(SOE) group (n=11)and stroke of other undemonstrated etiology(SUE) group(n=51) according to the TOAST classification. Plasma homocysteine and D-diamer were determined within the first 24 hours of admission, the differences in subgroups and control group(n=121) were analyzed. Results:Plasma homocysteine levels in LAA group were signficantly higher than other groups(P<0.05), no differences in non-LAA groups(P>0.05);Plasma D-diamer levels in CE group were significant higher than other groups(P<0.05), no differences in non-CE groups(P>0.05). Conclusions: Plasma homocysteine and D-diamer level are associated with subtypes of acute cerebral infarction, and it contributed to early classification diagnosis and individual treatment of patients with acute cerebral infarction.

Keywords


Cerebralinfarction; Homocysteinemia(Hcy); D-dimer;TOASTclassification

Full Text:

PDF (简体中文)


DOI: http://dx.doi.org/10.14725/gjtm.v2n2a469

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

Global Journal of Traditional Medicine 

ISSN 2308-5665 (Print)  ISSN ****-**** (Online)