Discussing the generalized model of cerebral infarction based on the perforating artery-neural tissue units

Abstract

This paper anatomizes the definition of perforating artery disease, and generalizes the connotation of perforating artery. Then a medical hypothesis is proposed that the perforating artery-neural tissue units can be regarded as basic unit for the formation of cerebral infarction, which contributes to arouse new thinking of cerebral infarction model. This paper breaks through conventional mode of thinking and analyzes the models of cerebral infarction based on the perforating artery-neural tissue units. The models of cerebral infarction were finally classified into three categories: single-perforating artery disease, multi-perforating artery disease and extensive-perforating artery disease. This classification would contribute to understand the formation of cerebral infarction from a new perspective, and to use the characteristics information of cerebral infarction image model to guide the etiology classification of cerebral infarction, pathogenesis understanding and treatment options.