Application of epinephrine in knee arthroscopy

Yan-yu Lin, Qiang Li, Jia-peng Zheng


Objective: To explore the preparation method of epinephrine for knee arthroscopy, and to find the best temperature and concentration. Methods: A total of 60 cases of knee arthroscopy in our department, from September 2011 to January 2013, was divided into 6 groups. Condition for group A: low temperature (8℃), and low concentration (3000ml saline+0.5ml epinephrine); Group B:low temperature, but high concentration (3000ml saline+1ml epinephrine); Group C: normal temperature (23℃), and low concentration; Group D: normal temperature (23℃), and high concentration; Group E: heating (37℃),but low concentration; Group F: heating (37℃),and high concentration. Each group was used for the operation, and the effect of hemostasis and the changes of vital signs of the patients were observed during the operation. Results: The bleeding amounts in Group C and Group E were more than other groups, and the red blood cell counts increased significantly in the flushing fluid of the two groups. The effect of hemostasis in Group A, B, D and F was good. The patients in Group A, B, C, and D experienced a rapid rise or fall in temperature due to massive application of douching fluid. The patients in Group F didn’t experience much interference. Conclusion: The application of heating epinephrine imposes less interference to the patients’ vital signs during knee arthroscopy. Moreover, the effect of hemostasis is good, and the safety of the operation improved. It is worth to be popularized.


Epinephrine; Adrenaline; Perfusion fluid; Hemostasis

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Global Journal of Advanced Nursing Practice

ISSN 2375-8422(Print)  ISSN 2375-8430(Online)