Mechanism of ORF128 protein in activating NF-KB and escaping the host immune

Yan-ge Wang, Qiu-mei Wei, Yu-lin He

Abstract


To elucidate whether ORF128 protein is an important protein of ORFV escaping from host immune response by analyzing the mechanism of orf virus ORF128 protein in NF- k B signaling pathway. It is important to understand the pathogenesis of ORFV and the relationship between antiviral and antiviral inhibition of host and virus, which lay a theoretical foundation for the development of new antiviral drugs and vaccines for ORFV.


Keywords


Orf virus; ORF128 protein; NF- kappa B

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References


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DOI: http://dx.doi.org/10.14725/gapr.v4n1a1727

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